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R and .NET Bio

Aug 4, 2012 at 12:32 AM

This is something I have been wondering about for a while. There are a few links that might make such a thing possible, including the existing RDotNet project here This project manages a number of dependencies in a clean fashion, allowing you to get started by just referencing a single DLL. 

But this post is prompted by a tweet from @dsyme posting a link to an F# type provider for R built on top of this project. The code is in its infancy, but this is the sort of bridge that might just allow a clean mix of tools and technologies: 

  • functional syntax for quickly setting up data extraction and parsing, maybe applying some transformations across the collection 
  • the .NET Bio libraries to do all that stuff efficiently, and to store the resulting objects in well-chosen data structures. 
  • ready integrated access to R to do specific data analysis and ML. 

Has anyone out there tried to get .NET Bio Sequence objects to play nicely with R and Bioconductor? 

The post referred to is here:

The code example isn't very viewable, so I went to the github repo. The example is very clear:


Anyone interested in pursuing this? 




Aug 6, 2012 at 5:01 PM

How about Sho? (

Aug 15, 2012 at 6:23 AM

sorry for the delay. I looked at this the day after you sent it and then got busy. It seems a very good project, but I tend to feel that R has such a community behind it that if we were to focus our attention in the one area, R would be a better choice. It just has so much traction, and so many libraries. 

It will be interesting to see what sort of uses people make of the F# and R links, however, and of course it would be good to see some more contributions to this and the other future threads.