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.NET Bio 1.0

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Downloads: 4952
Change Set: 70528
Released: Oct 12, 2011
Updated: Dec 21, 2011 by Rickbe
Dev status: Stable Help Icon

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Documentation .NET Bio V1 Training Materials
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Release Notes

.NET Bio 1.0 - A bioinformatics toolkit built using the Microsoft 4.0 .NET Framework to help developers, researchers, and scientists. This open-source platform is a library of commonly-used bioinformatics functions. Applications written to .NET Bio can be implemented in a variety of .NET languages, including C#, F#, Visual Basic® .NET, and IronPython.

Microsoft Research Sequence Assembler - The Sequence Assembler application is a demonstration application useful only with small datasets, intended for use by biologist and laboratory technicians who are responsible for managing next-generation genomic sequencing data for alignment, assembly, and/or BLAST identification. Though many other full-featured applications provide similar functionality, the primary goal of offering this application is to expose the capabilities available in .NET Bio. When coupled with the rich user interface (UI) elements that the Windows Presentation Foundation supports, the Sequence Assembler provides a unique combination of advanced application interface, controls, and visualization of the data. These features can be useful to scientists, researchers, and clinicians who work with genomic data, but more importantly, the Sequence Assembler is a full-featured sample application that can be extended, modified, and expanded to meet the needs of researchers.

Microsoft Research Biology Extension for Excel - The Microsoft Research Biology Extension for Excel is a sample application for biologists who are interested in, or already using, Microsoft Excel for their research. The extensible nature of Excel lends itself to the creation of a custom ribbon component labeled “Bioinformatics” in the top menu bar of the application. Through this customization, all the usual features of Excel remain available, but the biologist now has access to additional dedicated bioinformatics features. The Biology Extension can be further extended by developers to use other features in .NET Bio. Developers can write custom bioinformatics applications by using the libraries of .NET Bio and can add UI elements for those applications to the Biology Extension.

.NET Bio V 1.0 Training Materials
This is a zipped folder of the self guided 8 module course. The topics covered by this course are:
  1. Introduction to .NET Bio and Command Line overview of .NET Bio, its intended scenarios, and included command-line tools
  2. Programming with Visual Studio 2010 and C#...comprehensive introduction to the Microsoft Visual Studio and .NET 4
  3. Building Applications with .NET overview of the types that are included in the .NET Bio .dll
  4. Working with Sequences...examines the Sequence data type in .NET Bio
  5. Parsers and Formatters...explores .NET Bio’s built-in sequence parsers, formatters, alphabets, and encoders
  6. Algorithms...examines the algorithms that are defined in .NET Bio for gene sequence alignment
  7. Web Services...introduces using web services such as BLAST, and ClustalW with .NET Bio
  8. Sho...utilizing Sho scripts as a data analysis tool

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